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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4295eeb39b7c1c5114ea67dc19cd85c5aded55d1f4383dbf252c72de1559154' 
  AND token = 'XGC4vFDX7e8P99emxpRvTPu9bYk7lgYlNcNb9kJU8ss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}