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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c45776eb6752c1e278e50d3bc93db37974396f0ebcab49cbcd7e3a2566141a0' 
  AND token = 'TDz50kbqjaMSRqTFfNJqDUI62eYMFIKi77zphK99Wug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}