SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0e8e1a52d0ee232096acf085165f2346367c63e44fdc4835b3349c29b91bbc4' 
  AND token = 'tDid6BbKGm7pSC1rDspVIW1cg+3W/vFJ46W3jmOazzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}