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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e656122f80a15e225a294a07e46d0c03010635019566bee2154905ed10ab6d76' 
  AND token = 'usB1Pn7RU3VCj9Vt9o6ES75jSqDJQAptZs77OA8/LOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}