SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15b58d1667987f3a6a567e9c62aed2327ec5e7604b64227834e68b1afac502a5' 
  AND token = 'tGUTY7AFVPkLTMYMiGjWnDlYGz23GJmEp4nToo0BKuo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}