SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f80423bb4c217478fdf4194e5b1234a8c3e1ed04a0fefc17f7217f453d0f94b2' 
  AND token = '9rskQm8bs3q2bxHI6V1TVpVhvcuKcYEjTjfgEcBGwtE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}