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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54d6d6f0db008f07447585b2ee5aae95a3c9bf1789ecf0c8c8d3280a14ca414c' 
  AND token = 'uWnXu4DqjtTZ5b6IjtbEApMIpYdWY/cavaWHztsV8Qg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}