SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7118bb0532d40992c3e64967cbd1493c366c5de998abce6aa13612d709d86fa3' 
  AND token = 'K7D5tCbOXelMnwWKyhdGunZAK4P6UImonjcMDzd7C9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}