SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0de98a88488839a0937a8696b6aa197d1364b110600653588253391acbfd1e33' 
  AND token = 'C7dCCzD9nq27mPYhvpLODQELoVapk5pqEFKqkm/VWIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}