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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ea8bd72e6cd94fc597286a5f375cad29f7bf0f0a1e1040aa493e4206cec9c76' 
  AND token = 'M/yGbOLfK0V6QSMSjD8jwfmrGN9C1ySXaGzY648N+Y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}