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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49fa30bdf5f0f4be458f099735880cd79b2d9aa9aec167a5ef9aabb27025235f' 
  AND token = 'M/TREh7Biqbkz9z9Dm66wwqf8cBoxCfjHIkBOB/IM+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}