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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c68e3878ea4b4669dcd7f58009409208de96f4535b2ff110ab09e934e622a890' 
  AND token = 'I2KzkU1fmZZU08tT+we/9H+jwuaqm7cv5OPcd1jAlUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}