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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49117fec657ca83489f3a39ef968ff1dc40cf3eb383dc8f1a41f0bdc664160d6' 
  AND token = '49oSu8+1b8tdNqopzJqrMEwOj6h1DM8VxMqeoV2BdzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}