SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19afbbae62d6d313883d95f88711a1660c5b5e68a31327486a6a7c797fad091c' 
  AND token = 'V0U7BnutK4VIRfUm/h220lhvmXDsBc39VU7tLHxF6yQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}