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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '943105a23c7f839f7e79b23698d7757c605c0f9082ba6cf8b6ffdab11ec0957f' 
  AND token = '5eYDW0LNcAyLdHQXlQGSXpmETHK6WMkyWuRvZDBrNFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}