SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10fbd5b2f498e2d0e693da52da3ec0e2433232ed82625bd72f14a28aefe8911d' 
  AND token = 'yKUowUyrKf7hcl/99EloLfwT7++eigTWgc22rBMKzL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}