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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '62491cc608f64be97b7c7faa4303b400a0d80fe5fbd2a806592fccea64022d46' 
  AND token = 'FY3idD40WNmb2PZp5nCKKRczsPvm6HOgalf7BvTatPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}