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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d0c4c27010222eb0710b3d8cf101730a61e83ea12fc2cf2b0311124f0f2da1c' 
  AND token = '7OO1VFlOrUU1vNtPrbZV/RLuAUDwPRmYrUn5k0vCnlY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}