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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '275e75c3f9a17bfa11b7cf3b7de1a94e8a912b9168e7ee2f0965c4293143ece1' 
  AND token = 'ETKV13+r3yXCFA/SMqwZbnNosbBrnbJ9xmxoVu2K6fQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}