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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dd9e6a6cadd9936296a0ee24d2e67a59acf1bc58a933a1c36def00d06db5b73' 
  AND token = 'jauFB/ozgKU1Bagf8RVOKW5Wj4I8iPby4ZEuJXPynYY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}