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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '346c9c80168fe80db8a24e4fdfec0d5e842227d3697f6aa35d4d9603e0e1b4e9' 
  AND token = 'xk5K6LoERfq9xPs1HLMfb4kdBdg4lbK5gmXlCXPRTh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}