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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '393a11c5c2e26593ef8538c1abb26811aec5d7301aa89822ef5d03c3ab3e1167' 
  AND token = 'WvfvTMmkgbaw8k6L5NtYPLp7ka/k4S50KGn+X8Vhnk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}