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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c72075a44b153bc9880275c0517988e83a8bed6dc8736a1ab3a1375eb7be56e' 
  AND token = 'lXzioWm1oI9YCGZqoanlrTEkERgkX+t03pLQJLyh+Gg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}