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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed2d98c1fdb60b6941b5f0346f34faf68fdd6e27cd55f949d29358f5f8605657' 
  AND token = 'XoWcp1jiGsyCCncTdsaCDl3lTAcxcfSASJBHqrPpWsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}