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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c224a378943f81d1fb198ac1fdcbe4d24782bf326caeb64711117105ed745365' 
  AND token = 'XONgPqO1fbohHV5FBwjx9LpH3nttieM9C0WD5OWfqWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}