SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43a729ee597c5f050c16f3d074cd54d989c34b4fa180e2a6c6e024ea2a8f5aae' 
  AND token = 'Vim8ppBq7lGRpNCpHidE9Yk7F4eyyd3hLaJC5qQHbSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}