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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d8a873d32e262340ea6accfc1667a1b190b4241db37b7b458346e1ed7a440e8' 
  AND token = 'ZZUf4uxMRjoM0RdQ8EyorYlKKv4FiuzEIWqdvH77Oqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}