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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae9701f7b1364b4700a953ba782c56c46b6824901cbd64801605f115ae28490e' 
  AND token = 'Y6oM2nOawasSTLnSRQiiSrvkPW6nwUoTT2TP/AJn2V4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}