SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3464de69c2e0447e38572480e414b093d939b04f379ab4c1d8ce068b58277eaa' 
  AND token = 'zEGaSX41d4u7JiF/Jg3ql4W7Q8ftDTlBvKPNTJDEXz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}