SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e6c93b76cce73192336d6f53a1ec89b60ad051a82a66fb3271ddcbf39adb64a' 
  AND token = '11Ch3KkEcNMEMuYjEypADZZ1G6p16nsRUwVozV/9ddI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}