SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6af1f293dc42aea648e72ca62e56f7936f8bd83e03d97d2067b3ddd4e8e88123' 
  AND token = 'vKLhpaNyxnZGfbGqxeRcVqtDgGFQoSuCO+k5YOHOic0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}