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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49e6dd84c2fb336e7531e1689ebc3eac860270475f4b861290c4ea94099b4b6d' 
  AND token = 'ANq/CP/Gcxjr73jcDQeCoumLeojWH8GoIrbj4fm4UGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}