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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28d38852c8401e9c65b257acc71c87b6f8d3dab169d1c8fc7c8e493eb134290b' 
  AND token = 'CZd9eh4ugeURnYD8S9sHOC4KNRXsjf7HodKxGrpYEqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}