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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8a8d342c3394d0c320bdcf45b969af22ed1a8445414f2e65ee2a9157b0bea4f' 
  AND token = 'TfsHXPV79HeUosQCwf7AoaCFNXavdjoDDoUen/LllX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}