SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6b45e52809efc6c4f5a2a4cd27030620ca627325139a4790cec2cf5c77b7376' 
  AND token = 'KsvVT+nJw0JxBhy+rXf2Lmr2uFmqtlmHCV5uEZsuTDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}