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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc28f3b73093fc209e05469f2bd34a63cb8b7418e57e428ac5099826994073b9' 
  AND token = 'AxrXWW4UsrncIVb3UyB8MRzHjoX5lr5CVpHsgZU7lf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}