SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a90876942c56d1486937d459b2bb03548ec1f3d5611ff4a164d718228d03f5dd' 
  AND token = 'AEKW5HaK5It+8/61wUb20HXOUEt+0nGC32UXClCKGFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}