SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44035e8949aaac3e7ac686a1a9382037c3e4c3d0a95a7487e86fcca5b18c6952' 
  AND token = 'DWtgowjo9OP1hx/kZEqLQfLQS0K+MMx308rAxEgi094=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}