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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e115dc3e4f0fbc1e515553b89a486de4fe7b5672b19b1380aaf33576c9322654' 
  AND token = '8WgO7L5BG1qQcwwElUHW4WGxS2kP9XfQo4RRmWLPrV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}