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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c151f1b9df7b5afbc796e4e5f1907c79346abe1d7d57f292c6b316c6ef6ec8a' 
  AND token = 'FSL3OFOzIgXzrXic07aYaKEs3YogU4pNN4bJAadRNwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}