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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'deab7ae99ca54fad11e1a33dddb489246837236d05874f69e53bb74e3d641a9f' 
  AND token = '4IWbFQEeO5SG1uQuoup8bo7tyF1yzjQZCsQZTuPRhHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}