SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c8da8b130caadc8d04d245e73944a72d1e4af06c1db83274097cbb562ea9615' 
  AND token = 'ZVJBhxRirTOOwZVbahMOCb4CGvYOZ3dXczByTDrB6aE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}