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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63ba6302a740a5e2ea885d4e3b13ab8999c86a647f43e5b50e29cc3925d34b75' 
  AND token = 'UXx6EfBnffxw1uw9WpJI4hB+9DbNUofg3Yws7YxSUvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}