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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eee7225bc81b90a42565a108e61ce3ab0013c8f2e19487c3d4cc4813aabe1171' 
  AND token = 'zoILMePjbpE+6l0HexkVuUhfmC4PmldQa3Sx7m5NkUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}