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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f348b680655283b4ca2ed350f43bf6caabc7c0f3bd349ab0c1e01862a2dc5cdf' 
  AND token = 'JwEZCDTXx0vR5ackG75x7VjOOrPRKKdQceWcBhhl4WI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}