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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d8abc29900f8aa9d426209fd2c3c0c41bf28871ec518fc5dbbbb7cd7597053f' 
  AND token = 'XiYHRwnOsKTbnTtCjFC9dEPORQC22f8NlIAVygHOccE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}