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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b352d24e7d95787e774b6358d57a7a84b88a91d6da171956546129976e2d055b' 
  AND token = 'rlkuWJc6gnnXcgy+xx3txTFPOo5tbjv+DGjV5eOX1c8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}