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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f5a75a73eb1a6029f0c72075b634d99b7177d8668fcb3266e59e45e0b1f8571' 
  AND token = 'CYhP0ekuaRANH5X7hQGUXNSimJUQekZiasoBryVoEXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}