SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff07397f08c5f64a0de970b32171beb5089468a75c32af59373126110571ada8' 
  AND token = 'VNQcyMVJ3sY1/bNtB+faQ4MkIq+jv0FjUR8cHLPvtqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}