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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0bedcc30f4c35de1c458b8b300b33b35a04bb8eb8446f65eb34590b8f32f9a37' 
  AND token = 'KPUu669nsy4diT1fRKhoDD4A6E2RUw6AsV+vRbhkj/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}